HPV Target gene Detail Information

> AXDND1 Gene Search Result

Gene Information

Gene Name	AXDND1
Gene ID	126859
Gene Full Name	axonemal dynein light chain domain containing 1
Gene Alias	C1orf125
Transcripts	ENSG00000162779
Virus	HPV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q5T1B0
HGNC ID	HGNC:26564
VEGA ID	OTTHUMG00000035266
String ID	9606.ENSP00000356590
PharmGKB ID	PA142672443

Target gene [AXDND1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5000746	chr1	33	10	48	91	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE140662 (GEO)	Condyloma Acuminatum	8	Condyloma acuminata (HPV+)(5), Skin(3)
GSE55546 (GEO)	Oropharyngeal squamous cell carcinoma	16	Oropharyngeal cancers (HPV+)(12), Normal (4)
GSE55544 (GEO)	Oropharyngeal squamous cell carcinoma	23	Oropharyngeal cancers HPV Active (11), Oropharyngeal cancers HPV Inactive (4), Oropharyngeal cancers HPV Negative (8)
GSE55542 (GEO)	Oropharyngeal squamous cell carcinoma	36	Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)

> Dataset: GSE140662
HeatMap of cell type fractions in all samples	Lollipop of AXDND1 expression and immune infiltrating cell level correlation result in HPV+ samples
AXDND1 expression: Low -> High

> Dataset: GSE55546
HeatMap of cell type fractions in all samples	Lollipop of AXDND1 expression and immune infiltrating cell level correlation result in HPV+ samples
AXDND1 expression: Low -> High

> Dataset: GSE55544
HeatMap of cell type fractions in all samples	Lollipop of AXDND1 expression and immune infiltrating cell level correlation result in HPV+ samples
AXDND1 expression: Low -> High

> Dataset: GSE55542
HeatMap of cell type fractions in all samples	Lollipop of AXDND1 expression and immune infiltrating cell level correlation result in HPV+ samples
AXDND1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).