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HPV Target gene Detail Information

> AWAT1 Gene Search Result


Gene Information
Gene Name AWAT1
Gene ID 158833
Gene Full Name acyl-CoA wax alcohol acyltransferase 1
Gene Alias DGA2; DGAT2L3
Transcripts ENSG00000204195
Virus HPV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Enzymes, Predicted membrane proteins
Uniport_ID Q58HT5
HGNC ID HGNC:23252
VEGA ID OTTHUMG00000021773
OMIM ID 300924
String ID 9606.ENSP00000363645
PharmGKB ID PA164716409
Target gene [AWAT1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5002275 chrX 8 5 13 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE140662 (GEO) Condyloma Acuminatum 8 Condyloma acuminata (HPV+)(5), Skin(3)
GSE55546 (GEO) Oropharyngeal squamous cell carcinoma 16 Oropharyngeal cancers (HPV+)(12), Normal (4)
GSE55544 (GEO) Oropharyngeal squamous cell carcinoma 23 Oropharyngeal cancers HPV Active (11), Oropharyngeal cancers HPV Inactive (4), Oropharyngeal cancers HPV Negative (8)
GSE55542 (GEO) Oropharyngeal squamous cell carcinoma 36 Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE140662

HeatMap of cell type fractions in all samples Lollipop of AWAT1 expression and immune infiltrating cell level correlation result in HPV+ samples
AWAT1 expression: Low -> High

> Dataset: GSE55546

HeatMap of cell type fractions in all samples Lollipop of AWAT1 expression and immune infiltrating cell level correlation result in HPV+ samples
AWAT1 expression: Low -> High

> Dataset: GSE55544

HeatMap of cell type fractions in all samples Lollipop of AWAT1 expression and immune infiltrating cell level correlation result in HPV+ samples
AWAT1 expression: Low -> High

> Dataset: GSE55542

HeatMap of cell type fractions in all samples Lollipop of AWAT1 expression and immune infiltrating cell level correlation result in HPV+ samples
AWAT1 expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of AWAT1 expression and immune infiltrating cell level correlation result in HPV+ samples
AWAT1 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).