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HBV Target gene Detail Information

> AUTS2 Gene Search Result


Gene Information
Gene Name AUTS2
Gene ID 26053
Gene Full Name AUTS2, activator of transcription and developmental regulator
Gene Alias MRD26; FBRSL2
Transcripts ENSG00000158321
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;Cytosol;
HPA Protein Class Info Disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID Q8WXX7
HGNC ID HGNC:14262
VEGA ID OTTHUMG00000023865
OMIM ID 607270
String ID 9606.ENSP00000344087
PharmGKB ID PA134863175
Target gene [AUTS2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1004934 chr7 47 12 6 65 View
1010173 chr7 9 4 13 View
1010686 chr7 11 11 View
1011114 chr7 10 10 View
1011115 chr7 10 10 View
1011380 chr7 1 6 2 9 View
1011957 chr7 3 5 8 View
1013897 chr7 2 1 1 4 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of AUTS2 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
AUTS2 expression: Low -> High
Lollipop of AUTS2 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of AUTS2 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of AUTS2 expression and immune infiltrating cell level correlation result in HBV+ samples
AUTS2 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).