HTLV1 Target gene Detail Information

> ATXN7L3 Gene Search Result

Gene Information

Gene Name	ATXN7L3
Gene ID	56970
Gene Full Name	ataxin 7 like 3
Transcripts	ENSG00000087152
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Nuclear speckles;Plasma membrane;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q14CW9
HGNC ID	HGNC:25416
VEGA ID	OTTHUMG00000181812
OMIM ID	619010
String ID	9606.ENSP00000397259
PharmGKB ID	PA134991793

Target gene [ATXN7L3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6009816	chr17	34			34	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of ATXN7L3 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ATXN7L3 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of ATXN7L3 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ATXN7L3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).