HTLV1 Target gene Detail Information

> ATXN7L3 Gene Search Result


Gene Information
Gene Name ATXN7L3
Gene ID 56970
Gene Full Name ataxin 7 like 3
Transcripts ENSG00000087152
Virus HTLV1
Gene Type protein coding
HPA Location Info Nuclear speckles;Plasma membrane;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q14CW9
HGNC ID HGNC:25416
VEGA ID OTTHUMG00000181812
OMIM ID 619010
String ID 9606.ENSP00000397259
PharmGKB ID PA134991793
Target gene [ATXN7L3] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6009816 chr17 34 34 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of ATXN7L3 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ATXN7L3 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of ATXN7L3 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ATXN7L3 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).