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HIV Target gene Detail Information

> ATXN2 Gene Search Result


Gene Information
Gene Name ATXN2
Gene ID 6311
Gene Full Name ataxin 2
Gene Alias ATX2; SCA2; TNRC13
Transcripts ENSG00000204842
Virus HIV
Gene Type protein coding
HPA Location Info Cytosol;
HPA Protein Class Info Disease related genes, Predicted intracellular proteins
Uniport_ID Q99700
HGNC ID HGNC:10555
VEGA ID OTTHUMG00000133475
OMIM ID 601517
String ID 9606.ENSP00000366843
PharmGKB ID PA34968
Target gene [ATXN2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4000776 chr12 34 23 227 284 View
4001326 chr12 146 15 18 179 View
4001502 chr12 143 12 1 156 View
4001547 chr12 26 69 57 152 View
4001863 chr12 122 4 126 View
4002516 chr12 89 2 91 View
4003518 chr12 33 27 60 View
4005354 chr12 22 4 7 33 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of ATXN2 expression and immune infiltrating cell level correlation result in HIV+ samples
ATXN2 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of ATXN2 expression and immune infiltrating cell level correlation result in HIV+ samples
ATXN2 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).