HIV Target gene Detail Information

> ATXN10 Gene Search Result

Gene Information

Gene Name	ATXN10
Gene ID	25814
Gene Full Name	ataxin 10
Gene Alias	E46L; SCA10; HUMEEP
Transcripts	ENSG00000130638
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Plasma membrane;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	Q9UBB4
HGNC ID	HGNC:10549
VEGA ID	OTTHUMG00000150451
OMIM ID	611150
String ID	9606.ENSP00000252934
PharmGKB ID	PA34959

Target gene [ATXN10] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000084	chr22	67	739	386	1192	View
4000670	chr22	94	126	105	325	View
4008351	chr22	15			15	View
4012978	chr22	4			4	View
4013109	chr22	4			4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ATXN10 expression and immune infiltrating cell level correlation result in HIV+ samples
ATXN10 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ATXN10 expression and immune infiltrating cell level correlation result in HIV+ samples
ATXN10 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).