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HIV Target gene Detail Information

> ATXN1 Gene Search Result


Gene Information
Gene Name ATXN1
Gene ID 6310
Gene Full Name ataxin 1
Gene Alias ATX1; SCA1; D6S504E
Transcripts ENSG00000124788
Virus HIV
Gene Type protein coding
HPA Location Info Nucleoplasm;Cytosol;Nucleoli;
HPA Protein Class Info Disease related genes, Predicted intracellular proteins
Uniport_ID P54253
HGNC ID HGNC:10548
VEGA ID OTTHUMG00000014303
OMIM ID 601556
String ID 9606.ENSP00000244769
PharmGKB ID PA34958
Target gene [ATXN1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4000404 chr6 86 115 288 489 View
4000435 chr6 384 42 38 464 View
4000515 chr6 97 123 185 405 View
4008179 chr6 12 3 1 16 View
4008503 chr6 12 3 15 View
4010757 chr6 8 8 View
4013922 chr6 1 2 3 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of ATXN1 expression and immune infiltrating cell level correlation result in HIV+ samples
ATXN1 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of ATXN1 expression and immune infiltrating cell level correlation result in HIV+ samples
ATXN1 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).