HIV Target gene Detail Information

> ATRN Gene Search Result


Gene Information
Gene Name ATRN
Gene ID 8455
Gene Full Name attractin
Gene Alias MGCA; DPPT-L
Transcripts ENSG00000088812
Virus HIV
Gene Type protein coding
HPA Location Info Cytosol;Predicted to be secreted;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Plasma proteins, Predicted membrane proteins, Predicted secreted proteins
Uniport_ID O75882
HGNC ID HGNC:885
VEGA ID OTTHUMG00000031746
OMIM ID 603130
String ID 9606.ENSP00000262919
PharmGKB ID PA25178
Target gene [ATRN] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4006239 chr20 21 3 2 26 View
4008348 chr20 15 15 View
4010584 chr20 7 1 8 View
4015344 chr20 1 1 View
4016000 chr20 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of ATRN expression and immune infiltrating cell level correlation result in HIV+ samples
ATRN expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of ATRN expression and immune infiltrating cell level correlation result in HIV+ samples
ATRN expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).