HIV Target gene Detail Information

> ATR Gene Search Result

Gene Information

Gene Name	ATR
Gene ID	545
Gene Full Name	ATR serine/threonine kinase
Gene Alias	FRP1; MEC1; SCKL; FCTCS; SCKL1
Transcripts	ENSG00000175054
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Golgi apparatus;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins
Gene Function	Suppressor gene
Uniport_ID	Q13535
HGNC ID	HGNC:882
VEGA ID	OTTHUMG00000159234
OMIM ID	601215
String ID	9606.ENSP00000343741
PharmGKB ID	PA74

Target gene [ATR] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003243	chr3	65			65	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ATR expression and immune infiltrating cell level correlation result in HIV+ samples
ATR expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).