HBV Target gene Detail Information

> ATP8B1 Gene Search Result

Gene Information

Gene Name	ATP8B1
Gene ID	5205
Gene Full Name	ATPase phospholipid transporting 8B1
Gene Alias	BRIC; FIC1; ICP1; PFIC; ATPIC; PFIC1
Transcripts	ENSG00000081923
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;Plasma membrane;Nuclear bodies;Nucleoplasm;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID	O43520
HGNC ID	HGNC:3706
VEGA ID	OTTHUMG00000180255
OMIM ID	602397
String ID	9606.ENSP00000445359
PharmGKB ID	PA265

Target gene [ATP8B1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1000930	chr18	869	189	208	1266	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of ATP8B1 expression and immune infiltrating cell level correlation result in HBV+ samples
ATP8B1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).