HIV Target gene Detail Information

> ATP7A Gene Search Result


Gene Information
Gene Name ATP7A
Gene ID 538
Gene Full Name ATPase copper transporting alpha
Gene Alias MK; MNK; DSMAX; SMAX3
Transcripts ENSG00000165240
Virus HIV
Gene Type protein coding
HPA Location Info Golgi apparatus;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID Q04656
HGNC ID HGNC:869
VEGA ID OTTHUMG00000021885
OMIM ID 300011
String ID 9606.ENSP00000345728
Drugbank ID BE0003666
PharmGKB ID PA72
Target gene [ATP7A] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4005214 chrX 18 10 7 35 View
4015487 chrX 1 1 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of ATP7A expression and immune infiltrating cell level correlation result in HIV+ samples
ATP7A expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).