HIV Target gene Detail Information

> ATP7A Gene Search Result

Gene Information

Gene Name	ATP7A
Gene ID	538
Gene Full Name	ATPase copper transporting alpha
Gene Alias	MK; MNK; DSMAX; SMAX3
Transcripts	ENSG00000165240
Virus	HIV
Gene Type	protein coding
HPA Location Info	Golgi apparatus;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID	Q04656
HGNC ID	HGNC:869
VEGA ID	OTTHUMG00000021885
OMIM ID	300011
String ID	9606.ENSP00000345728
Drugbank ID	BE0003666
PharmGKB ID	PA72

Target gene [ATP7A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4005214	chrX	18	10	7	35	View
4015487	chrX		1		1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ATP7A expression and immune infiltrating cell level correlation result in HIV+ samples
ATP7A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).