HBV Target gene Detail Information

> ATP6V1C1 Gene Search Result


Gene Information
Gene Name ATP6V1C1
Gene ID 528
Gene Full Name ATPase H+ transporting V1 subunit C1
Gene Alias VATC; Vma5; ATP6C; ATP6D
Transcripts ENSG00000155097
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;Cytosol;
HPA Protein Class Info FDA approved drug targets, Predicted intracellular proteins, Transporters
Uniport_ID P21283
HGNC ID HGNC:856
VEGA ID OTTHUMG00000164761
OMIM ID 603097
String ID 9606.ENSP00000379203
Drugbank ID BE0004525; BE0008669
PharmGKB ID PA25156
Target gene [ATP6V1C1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1000611 chr8 1734 62 1 1797 View
1000659 chr8 1610 62 1 1673 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ATP6V1C1 expression and immune infiltrating cell level correlation result in HBV+ samples
ATP6V1C1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).