HIV Target gene Detail Information

> ATP6V1B2 Gene Search Result


Gene Information
Gene Name ATP6V1B2
Gene ID 526
Gene Full Name ATPase H+ transporting V1 subunit B2
Gene Alias DOOD; HO57; VATB; VPP3; Vma2; ZLS2; ATP6B2; ATP6B1B2
Transcripts ENSG00000147416
Virus HIV
Gene Type protein coding
HPA Location Info Vesicles;
HPA Protein Class Info Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Transporters
Uniport_ID P21281
HGNC ID HGNC:854
VEGA ID OTTHUMG00000131073
OMIM ID 606939
String ID 9606.ENSP00000276390
Drugbank ID BE0003813; BE0008669
PharmGKB ID PA25155
Target gene [ATP6V1B2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4012360 chr8 4 1 5 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of ATP6V1B2 expression and immune infiltrating cell level correlation result in HIV+ samples
ATP6V1B2 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of ATP6V1B2 expression and immune infiltrating cell level correlation result in HIV+ samples
ATP6V1B2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).