HIV Target gene Detail Information

> ATP6V1B2 Gene Search Result

Gene Information

Gene Name	ATP6V1B2
Gene ID	526
Gene Full Name	ATPase H+ transporting V1 subunit B2
Gene Alias	DOOD; HO57; VATB; VPP3; Vma2; ZLS2; ATP6B2; ATP6B1B2
Transcripts	ENSG00000147416
Virus	HIV
Gene Type	protein coding
HPA Location Info	Vesicles;
HPA Protein Class Info	Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Transporters
Uniport_ID	P21281
HGNC ID	HGNC:854
VEGA ID	OTTHUMG00000131073
OMIM ID	606939
String ID	9606.ENSP00000276390
Drugbank ID	BE0003813; BE0008669
PharmGKB ID	PA25155

Target gene [ATP6V1B2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4012360	chr8	4	1		5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ATP6V1B2 expression and immune infiltrating cell level correlation result in HIV+ samples
ATP6V1B2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ATP6V1B2 expression and immune infiltrating cell level correlation result in HIV+ samples
ATP6V1B2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).