HTLV1 Target gene Detail Information

> ATP6V1B1 Gene Search Result

Gene Information

Gene Name	ATP6V1B1
Gene ID	525
Gene Full Name	ATPase H+ transporting V1 subunit B1
Gene Alias	VATB; VMA2; VPP3; RTA1B; ATP6B1
Transcripts	ENSG00000116039
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Nuclear membrane;Nucleoplasm;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	P15313
HGNC ID	HGNC:853
VEGA ID	OTTHUMG00000129711
OMIM ID	192132
String ID	9606.ENSP00000234396
Drugbank ID	BE0010350; BE0008669
PharmGKB ID	PA25154

Target gene [ATP6V1B1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6003436	chr2	57	43	60	160	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of ATP6V1B1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ATP6V1B1 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of ATP6V1B1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ATP6V1B1 expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of ATP6V1B1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ATP6V1B1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).