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HTLV1 Target gene Detail Information

> ATP6V1A Gene Search Result


Gene Information
Gene Name ATP6V1A
Gene ID 523
Gene Full Name ATPase H+ transporting V1 subunit A
Gene Alias HO68; VA68; VPP2; Vma1; ARCL2D; ATP6A1; IECEE3; ATP6V1A1
Transcripts ENSG00000114573
Virus HTLV1
Gene Type protein coding
HPA Location Info Cytosol;Vesicles;Nucleoplasm;
HPA Protein Class Info Disease related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters
Uniport_ID P38606
HGNC ID HGNC:851
VEGA ID OTTHUMG00000159295
OMIM ID 607027
String ID 9606.ENSP00000273398
Drugbank ID BE0003569; BE0008669
PharmGKB ID PA25152
Target gene [ATP6V1A] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6011417 chr3 24 1 1 26 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of ATP6V1A expression and immune infiltrating cell level correlation result in HTLV1+ samples
ATP6V1A expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of ATP6V1A expression and immune infiltrating cell level correlation result in HTLV1+ samples
ATP6V1A expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of ATP6V1A expression and immune infiltrating cell level correlation result in HTLV1+ samples
ATP6V1A expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).