HTLV1 Target gene Detail Information

> ATP6V0C Gene Search Result

Gene Information

Gene Name	ATP6V0C
Gene ID	527
Gene Full Name	ATPase H+ transporting V0 subunit c
Gene Alias	ATPL; VATL; VPPC; Vma3; ATP6C; ATP6L
Transcripts	ENSG00000185883
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Cytosol;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	P27449
HGNC ID	HGNC:855
VEGA ID	OTTHUMG00000128865
OMIM ID	108745
String ID	9606.ENSP00000329757
Drugbank ID	BE0010341; BE0008669
PharmGKB ID	PA25149

Target gene [ATP6V0C] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6004289	chr16	57	64		121	View
6009113	chr16	21	18		39	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of ATP6V0C expression and immune infiltrating cell level correlation result in HTLV1+ samples
ATP6V0C expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of ATP6V0C expression and immune infiltrating cell level correlation result in HTLV1+ samples
ATP6V0C expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of ATP6V0C expression and immune infiltrating cell level correlation result in HTLV1+ samples
ATP6V0C expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).