HTLV1 Target gene Detail Information

> ATP6V0C Gene Search Result


Gene Information
Gene Name ATP6V0C
Gene ID 527
Gene Full Name ATPase H+ transporting V0 subunit c
Gene Alias ATPL; VATL; VPPC; Vma3; ATP6C; ATP6L
Transcripts ENSG00000185883
Virus HTLV1
Gene Type protein coding
HPA Location Info Cytosol;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID P27449
HGNC ID HGNC:855
VEGA ID OTTHUMG00000128865
OMIM ID 108745
String ID 9606.ENSP00000329757
Drugbank ID BE0010341; BE0008669
PharmGKB ID PA25149
Target gene [ATP6V0C] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6004289 chr16 57 64 121 View
6009113 chr16 21 18 39 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of ATP6V0C expression and immune infiltrating cell level correlation result in HTLV1+ samples
ATP6V0C expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of ATP6V0C expression and immune infiltrating cell level correlation result in HTLV1+ samples
ATP6V0C expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of ATP6V0C expression and immune infiltrating cell level correlation result in HTLV1+ samples
ATP6V0C expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).