HTLV1 Target gene Detail Information

> ATP6V0A2 Gene Search Result

Gene Information

Gene Name	ATP6V0A2
Gene ID	23545
Gene Full Name	ATPase H+ transporting V0 subunit a2
Gene Alias	A2; RTF; TJ6; WSS; ARCL; J6B7; STV1; TJ6M; TJ6S; VPH1; ARCL2A; ATP6A2; ATP6N1D
Transcripts	ENSG00000185344
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Cytosol;Plasma membrane;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q9Y487
HGNC ID	HGNC:18481
VEGA ID	OTTHUMG00000168723
OMIM ID	611716
String ID	9606.ENSP00000332247
Drugbank ID	BE0010347; BE0008669
PharmGKB ID	PA38549

Target gene [ATP6V0A2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6000330	chr12	2044	29	17	2090	View
6001170	chr12	79	417	58	554	View
6006050	chr12	25	50	1	76	View
6030254	chr12	1			1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of ATP6V0A2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ATP6V0A2 expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of ATP6V0A2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ATP6V0A2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).