HIV Target gene Detail Information

> ATP2B4 Gene Search Result

Gene Information

Gene Name	ATP2B4
Gene ID	493
Gene Full Name	ATPase plasma membrane Ca2+ transporting 4
Gene Alias	MXRA1; PMCA4; ATP2B2; PMCA4b; PMCA4x
Transcripts	ENSG00000058668
Virus	HIV
Gene Type	protein coding
HPA Location Info	Plasma membrane;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID	P23634
HGNC ID	HGNC:817
VEGA ID	OTTHUMG00000035906
OMIM ID	108732
String ID	9606.ENSP00000350310
Drugbank ID	BE0010397
PharmGKB ID	PA25110

Target gene [ATP2B4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003478	chr1	40	19	1	60	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ATP2B4 expression and immune infiltrating cell level correlation result in HIV+ samples
ATP2B4 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ATP2B4 expression and immune infiltrating cell level correlation result in HIV+ samples
ATP2B4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).