HIV Target gene Detail Information

> ATP2A2 Gene Search Result

Gene Information

Gene Name	ATP2A2
Gene ID	488
Gene Full Name	ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
Gene Alias	DD; DAR; ATP2B; SERCA2
Transcripts	ENSG00000174437
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID	P16615
HGNC ID	HGNC:812
VEGA ID	OTTHUMG00000169327
OMIM ID	108740
String ID	9606.ENSP00000440045
Drugbank ID	BE0003477
PharmGKB ID	PA71

Target gene [ATP2A2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004779	chr12	36	3		39	View
4008329	chr12	12		3	15	View
4009493	chr12	9	2		11	View
4015254	chr12	1			1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ATP2A2 expression and immune infiltrating cell level correlation result in HIV+ samples
ATP2A2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ATP2A2 expression and immune infiltrating cell level correlation result in HIV+ samples
ATP2A2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).