HBV Target gene Detail Information

> ATP2A1 Gene Search Result


Gene Information
Gene Name ATP2A1
Gene ID 487
Gene Full Name ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
Gene Alias ATP2A; SERCA1
Transcripts ENSG00000196296
Virus HBV
Gene Type protein coding
HPA Location Info Endoplasmic reticulum;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID O14983
HGNC ID HGNC:811
VEGA ID OTTHUMG00000131760
OMIM ID 108730
String ID 9606.ENSP00000349595
Drugbank ID BE0003888
PharmGKB ID PA25105
Target gene [ATP2A1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1017599 chr16 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ATP2A1 expression and immune infiltrating cell level correlation result in HBV+ samples
ATP2A1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).