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HTLV1 Target gene Detail Information

> ATP1A3 Gene Search Result


Gene Information
Gene Name ATP1A3
Gene ID 478
Gene Full Name ATPase Na+/K+ transporting subunit alpha 3
Gene Alias RDP; AHC2; CAPOS; DYT12; ATP1A1
Transcripts ENSG00000105409
Virus HTLV1
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID P13637
HGNC ID HGNC:801
VEGA ID OTTHUMG00000137384
OMIM ID 182350
String ID 9606.ENSP00000444688
Drugbank ID BE0004972; BE0005047
PharmGKB ID PA64
Target gene [ATP1A3] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6016327 chr19 12 12 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of ATP1A3 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ATP1A3 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of ATP1A3 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ATP1A3 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of ATP1A3 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ATP1A3 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).