HIV Target gene Detail Information

> ATL2 Gene Search Result

Gene Information

Gene Name	ATL2
Gene ID	64225
Gene Full Name	atlastin GTPase 2
Gene Alias	aip-2; ARL3IP2; ARL6IP2; atlastin2
Transcripts	ENSG00000119787
Virus	HIV
Gene Type	protein coding
HPA Location Info	Endoplasmic reticulum;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q8NHH9
HGNC ID	HGNC:24047
VEGA ID	OTTHUMG00000102074
OMIM ID	609368
String ID	9606.ENSP00000368237
PharmGKB ID	PA164716322

Target gene [ATL2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001559	chr15	5	74	72	151	View
4002320	chr15	22	42	36	100	View
4002642	chr15	4	35	47	86	View
4003187	chr2	67			67	View
4003372	chr15	9	18	36	63	View
4006376	chr2	7	18		25	View
4012811	chr2	4			4	View
4013655	chr2	1	2		3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ATL2 expression and immune infiltrating cell level correlation result in HIV+ samples
ATL2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ATL2 expression and immune infiltrating cell level correlation result in HIV+ samples
ATL2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).