HIV Target gene Detail Information

> ATG5 Gene Search Result

Gene Information

Gene Name	ATG5
Gene ID	9474
Gene Full Name	autophagy related 5
Gene Alias	ASP; APG5; APG5L; hAPG5; SCAR25; APG5-LIKE
Transcripts	ENSG00000057663
Virus	HIV
Gene Type	protein coding
HPA Location Info	Centrosome;
HPA Protein Class Info	Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters
Uniport_ID	Q9H1Y0
HGNC ID	HGNC:589
VEGA ID	OTTHUMG00000016193
OMIM ID	604261
String ID	9606.ENSP00000358072
PharmGKB ID	PA24880

Target gene [ATG5] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002808	chr6	16	26	37	79	View
4006847	chr6	22			22	View
4009304	chr6	12			12	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ATG5 expression and immune infiltrating cell level correlation result in HIV+ samples
ATG5 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ATG5 expression and immune infiltrating cell level correlation result in HIV+ samples
ATG5 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).