HIV Target gene Detail Information

> ATG4D Gene Search Result

Gene Information

Gene Name	ATG4D
Gene ID	84971
Gene Full Name	autophagy related 4D cysteine peptidase
Gene Alias	APG4D; AUTL4; APG4-D
Transcripts	ENSG00000130734
Virus	HIV
Gene Type	protein coding
HPA Location Info	Mitochondria;Nucleoplasm;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins, Transporters
Uniport_ID	Q86TL0
HGNC ID	HGNC:20789
VEGA ID	OTTHUMG00000180582
OMIM ID	611340
String ID	9606.ENSP00000311318
PharmGKB ID	PA134907475

Target gene [ATG4D] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4011224	chr19	7			7	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ATG4D expression and immune infiltrating cell level correlation result in HIV+ samples
ATG4D expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ATG4D expression and immune infiltrating cell level correlation result in HIV+ samples
ATG4D expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).