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HBV Target gene Detail Information

> ATF7IP2 Gene Search Result


Gene Information
Gene Name ATF7IP2
Gene ID 80063
Gene Full Name activating transcription factor 7 interacting protein 2
Gene Alias MCAF2
Transcripts ENSG00000166669
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q5U623
HGNC ID HGNC:20397
VEGA ID OTTHUMG00000129749
OMIM ID 613645
String ID 9606.ENSP00000379808
PharmGKB ID PA134988230
Target gene [ATF7IP2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1003528 chr16 84 33 10 127 View
1400888 chr16 84 33 10 127 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of ATF7IP2 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
ATF7IP2 expression: Low -> High
Lollipop of ATF7IP2 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of ATF7IP2 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ATF7IP2 expression and immune infiltrating cell level correlation result in HBV+ samples
ATF7IP2 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).