HIV Target gene Detail Information

> ATF6 Gene Search Result

Gene Information

Gene Name	ATF6
Gene ID	22926
Gene Full Name	activating transcription factor 6
Gene Alias	ACHM7; ATF6A
Transcripts	ENSG00000118217
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Plasma proteins, Predicted membrane proteins, Transcription factors
Uniport_ID	P18850
HGNC ID	HGNC:791
VEGA ID	OTTHUMG00000023961
OMIM ID	605537
String ID	9606.ENSP00000356919
Drugbank ID	BE0004859; BE0004924
PharmGKB ID	PA25091

Target gene [ATF6] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4007833	chr1	13	4		17	View
4008055	chr1	9	7		16	View
4010658	chr1	8			8	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ATF6 expression and immune infiltrating cell level correlation result in HIV+ samples
ATF6 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ATF6 expression and immune infiltrating cell level correlation result in HIV+ samples
ATF6 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).