HIV Target gene Detail Information

> ATF6 Gene Search Result


Gene Information
Gene Name ATF6
Gene ID 22926
Gene Full Name activating transcription factor 6
Gene Alias ACHM7; ATF6A
Transcripts ENSG00000118217
Virus HIV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, Plasma proteins, Predicted membrane proteins, Transcription factors
Uniport_ID P18850
HGNC ID HGNC:791
VEGA ID OTTHUMG00000023961
OMIM ID 605537
String ID 9606.ENSP00000356919
Drugbank ID BE0004859; BE0004924
PharmGKB ID PA25091
Target gene [ATF6] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4007833 chr1 13 4 17 View
4008055 chr1 9 7 16 View
4010658 chr1 8 8 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of ATF6 expression and immune infiltrating cell level correlation result in HIV+ samples
ATF6 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of ATF6 expression and immune infiltrating cell level correlation result in HIV+ samples
ATF6 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).