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HBV Target gene Detail Information

> ASTN2 Gene Search Result


Gene Information
Gene Name ASTN2
Gene ID 23245
Gene Full Name astrotactin 2
Gene Alias bA67K19.1
Transcripts ENSG00000148219
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;Nucleoplasm;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID O75129
HGNC ID HGNC:17021
VEGA ID OTTHUMG00000021013
OMIM ID 612856
String ID 9606.ENSP00000354504
PharmGKB ID PA25076
Target gene [ASTN2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1002467 chr9 10 69 190 269 View
1003912 chr9 71 8 23 102 View
1007058 chr9 20 11 31 View
1010294 chr9 13 13 View
1019514 chr9 0 View
1019956 chr9 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of ASTN2 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
ASTN2 expression: Low -> High
Lollipop of ASTN2 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of ASTN2 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ASTN2 expression and immune infiltrating cell level correlation result in HBV+ samples
ASTN2 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).