HIV Target gene Detail Information

> ASPM Gene Search Result

Gene Information

Gene Name	ASPM
Gene ID	259266
Gene Full Name	abnormal spindle microtubule assembly
Gene Alias	ASP; MCPH5; Calmbp1
Transcripts	ENSG00000066279
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Plasma membrane;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q8IZT6
HGNC ID	HGNC:19048
VEGA ID	OTTHUMG00000036277
OMIM ID	605481
String ID	9606.ENSP00000356379
PharmGKB ID	PA38782

Target gene [ASPM] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4015937	chr1				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ASPM expression and immune infiltrating cell level correlation result in HIV+ samples
ASPM expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ASPM expression and immune infiltrating cell level correlation result in HIV+ samples
ASPM expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).