HIV Target gene Detail Information

> ASPM Gene Search Result


Gene Information
Gene Name ASPM
Gene ID 259266
Gene Full Name abnormal spindle microtubule assembly
Gene Alias ASP; MCPH5; Calmbp1
Transcripts ENSG00000066279
Virus HIV
Gene Type protein coding
HPA Location Info Cytosol;Plasma membrane;
HPA Protein Class Info Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID Q8IZT6
HGNC ID HGNC:19048
VEGA ID OTTHUMG00000036277
OMIM ID 605481
String ID 9606.ENSP00000356379
PharmGKB ID PA38782
Target gene [ASPM] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4015937 chr1 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of ASPM expression and immune infiltrating cell level correlation result in HIV+ samples
ASPM expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of ASPM expression and immune infiltrating cell level correlation result in HIV+ samples
ASPM expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).