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HBV Target gene Detail Information

> ASF1B Gene Search Result


Gene Information
Gene Name ASF1B
Gene ID 55723
Gene Full Name anti-silencing function 1B histone chaperone
Gene Alias CIA-II
Transcripts ENSG00000288210
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q9NVP2
HGNC ID HGNC:20996
VEGA ID OTTHUMG00000150401
OMIM ID 609190
String ID 9606.ENSP00000263382
PharmGKB ID PA134931112
Target gene [ASF1B] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1000459 chr19 2009 148 19 2176 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of ASF1B expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
ASF1B expression: Low -> High
Lollipop of ASF1B expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of ASF1B expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ASF1B expression and immune infiltrating cell level correlation result in HBV+ samples
ASF1B expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).