HIV Target gene Detail Information

> ASCC1 Gene Search Result

Gene Information

Gene Name	ASCC1
Gene ID	51008
Gene Full Name	activating signal cointegrator 1 complex subunit 1
Gene Alias	p50; CGI-18; SMABF2; ASC1p50
Transcripts	ENSG00000138303
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cytosol;
HPA Protein Class Info	Disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q8N9N2
HGNC ID	HGNC:24268
VEGA ID	OTTHUMG00000018434
OMIM ID	614215
String ID	9606.ENSP00000339404
PharmGKB ID	PA134974899

Target gene [ASCC1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001307	chr10	171	8	1	180	View
4010663	chr10	7	1		8	View
4016149	chr10				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ASCC1 expression and immune infiltrating cell level correlation result in HIV+ samples
ASCC1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ASCC1 expression and immune infiltrating cell level correlation result in HIV+ samples
ASCC1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).