HIV Target gene Detail Information

> ARPC2 Gene Search Result

Gene Information

Gene Name	ARPC2
Gene ID	10109
Gene Full Name	actin related protein 2/3 complex subunit 2
Gene Alias	ARC34; PRO2446; p34-Arc; PNAS-139
Transcripts	ENSG00000163466
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	O15144
HGNC ID	HGNC:705
VEGA ID	OTTHUMG00000133618
OMIM ID	604224
String ID	9606.ENSP00000295685
Drugbank ID	BE0004252
PharmGKB ID	PA24999

Target gene [ARPC2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4007559	chr2	15	3	1	19	View
4007852	chr2	17			17	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ARPC2 expression and immune infiltrating cell level correlation result in HIV+ samples
ARPC2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ARPC2 expression and immune infiltrating cell level correlation result in HIV+ samples
ARPC2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).