HIV Target gene Detail Information

> ARPC1B Gene Search Result

Gene Information

Gene Name	ARPC1B
Gene ID	10095
Gene Full Name	actin related protein 2/3 complex subunit 1B
Gene Alias	ARC41; PLTEID; p40-ARC; p41-ARC
Transcripts	ENSG00000130429
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Vesicles;
HPA Protein Class Info	Disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	O15143
HGNC ID	HGNC:704
VEGA ID	OTTHUMG00000154552
OMIM ID	604223
String ID	9606.ENSP00000389631
Drugbank ID	BE0004249
PharmGKB ID	PA24998

Target gene [ARPC1B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4005077	chr7	36			36	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ARPC1B expression and immune infiltrating cell level correlation result in HIV+ samples
ARPC1B expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ARPC1B expression and immune infiltrating cell level correlation result in HIV+ samples
ARPC1B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).