HIV Target gene Detail Information

> ARPC1B Gene Search Result


Gene Information
Gene Name ARPC1B
Gene ID 10095
Gene Full Name actin related protein 2/3 complex subunit 1B
Gene Alias ARC41; PLTEID; p40-ARC; p41-ARC
Transcripts ENSG00000130429
Virus HIV
Gene Type protein coding
HPA Location Info Cytosol;Vesicles;
HPA Protein Class Info Disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID O15143
HGNC ID HGNC:704
VEGA ID OTTHUMG00000154552
OMIM ID 604223
String ID 9606.ENSP00000389631
Drugbank ID BE0004249
PharmGKB ID PA24998
Target gene [ARPC1B] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4005077 chr7 36 36 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of ARPC1B expression and immune infiltrating cell level correlation result in HIV+ samples
ARPC1B expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of ARPC1B expression and immune infiltrating cell level correlation result in HIV+ samples
ARPC1B expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).