HTLV1 Target gene Detail Information

> ARNTL Gene Search Result

Gene Information

Gene Name	ARNTL
Gene ID	406
Gene Full Name	aryl hydrocarbon receptor nuclear translocator like
Gene Alias	TIC; JAP3; MOP3; BMAL1; PASD3; BMAL1c; bHLHe5
Transcripts	ENSG00000133794
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Vesicles;
HPA Protein Class Info	Predicted intracellular proteins, Transcription factors
Gene Function	Suppressor gene
Uniport_ID	O00327
HGNC ID	HGNC:701
VEGA ID	OTTHUMG00000150623
OMIM ID	602550
String ID	9606.ENSP00000384517
PharmGKB ID	PA24996

Target gene [ARNTL] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6000225	chr11	2115	287	444	2846	View
6003242	chr11	94	69	10	173	View
6006019	chr11	18	13	45	76	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of ARNTL expression and immune infiltrating cell level correlation result in HTLV1+ samples
ARNTL expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of ARNTL expression and immune infiltrating cell level correlation result in HTLV1+ samples
ARNTL expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of ARNTL expression and immune infiltrating cell level correlation result in HTLV1+ samples
ARNTL expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).