HBV Target gene Detail Information

> ARMC8 Gene Search Result


Gene Information
Gene Name ARMC8
Gene ID 25852
Gene Full Name armadillo repeat containing 8
Gene Alias GID5; VID28; S863-2; HSPC056
Transcripts ENSG00000114098
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;Cytosol;Vesicles;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q8IUR7
HGNC ID HGNC:24999
VEGA ID OTTHUMG00000159821
OMIM ID 618521
String ID 9606.ENSP00000420333
PharmGKB ID PA134984953
Target gene [ARMC8] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1010267 chr3 12 1 13 View
1404366 chr3 55 15 26 96 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of ARMC8 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
ARMC8 expression: Low -> High
Lollipop of ARMC8 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of ARMC8 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ARMC8 expression and immune infiltrating cell level correlation result in HBV+ samples
ARMC8 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).