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HBV Target gene Detail Information

> ARL8B Gene Search Result


Gene Information
Gene Name ARL8B
Gene ID 55207
Gene Full Name ADP ribosylation factor like GTPase 8B
Gene Alias Gie1; ARL10C
Transcripts ENSG00000134108
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q9NVJ2
HGNC ID HGNC:25564
VEGA ID OTTHUMG00000090463
OMIM ID 616596
String ID 9606.ENSP00000256496
PharmGKB ID PA134959531
Target gene [ARL8B] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1007777 chr3 14 10 24 View
1401009 chr3 14 10 24 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of ARL8B expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
ARL8B expression: Low -> High
Lollipop of ARL8B expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of ARL8B expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ARL8B expression and immune infiltrating cell level correlation result in HBV+ samples
ARL8B expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).