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HTLV1 Target gene Detail Information

> ARL5B Gene Search Result


Gene Information
Gene Name ARL5B
Gene ID 221079
Gene Full Name ADP ribosylation factor like GTPase 5B
Gene Alias ARL8
Transcripts ENSG00000165997
Virus HTLV1
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q96KC2
HGNC ID HGNC:23052
VEGA ID OTTHUMG00000017765
OMIM ID 608909
String ID 9606.ENSP00000366487
Drugbank ID BE0004627
PharmGKB ID PA134979161
Target gene [ARL5B] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6018993 chr10 8 8 View
6031139 chr10 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of ARL5B expression and immune infiltrating cell level correlation result in HTLV1+ samples
ARL5B expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of ARL5B expression and immune infiltrating cell level correlation result in HTLV1+ samples
ARL5B expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of ARL5B expression and immune infiltrating cell level correlation result in HTLV1+ samples
ARL5B expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).