HTLV1 Target gene Detail Information

> ARID5A Gene Search Result

Gene Information

Gene Name	ARID5A
Gene ID	10865
Gene Full Name	AT-rich interaction domain 5A
Gene Alias	MRF1; MRF-1; RP11-363D14
Transcripts	ENSG00000196843
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Nucleoli;
HPA Protein Class Info	Predicted intracellular proteins, Transcription factors
Uniport_ID	Q03989
HGNC ID	HGNC:17361
VEGA ID	OTTHUMG00000155229
OMIM ID	611583
String ID	9606.ENSP00000350078
PharmGKB ID	PA134937822

Target gene [ARID5A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6007917	chr2	32	18		50	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of ARID5A expression and immune infiltrating cell level correlation result in HTLV1+ samples
ARID5A expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of ARID5A expression and immune infiltrating cell level correlation result in HTLV1+ samples
ARID5A expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of ARID5A expression and immune infiltrating cell level correlation result in HTLV1+ samples
ARID5A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).