HIV Target gene Detail Information

> ARID3A Gene Search Result

Gene Information

Gene Name	ARID3A
Gene ID	1820
Gene Full Name	AT-rich interaction domain 3A
Gene Alias	DRIL1; DRIL3; BRIGHT; E2FBP1
Transcripts	ENSG00000116017
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cytosol;
HPA Protein Class Info	Predicted intracellular proteins, Transcription factors
Gene Function	Oncogene
Uniport_ID	Q99856
HGNC ID	HGNC:3031
VEGA ID	OTTHUMG00000182018
OMIM ID	603265
String ID	9606.ENSP00000263620
PharmGKB ID	PA27485

Target gene [ARID3A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004257	chr19	14	33		47	View
4004392	chr19	11	11	23	45	View
4014725	chr19	1	1		2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ARID3A expression and immune infiltrating cell level correlation result in HIV+ samples
ARID3A expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ARID3A expression and immune infiltrating cell level correlation result in HIV+ samples
ARID3A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).