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HBV Target gene Detail Information

> ARID1B Gene Search Result


Gene Information
Gene Name ARID1B
Gene ID 57492
Gene Full Name AT-rich interaction domain 1B
Gene Alias CSS1; OSA2; 6A3-5; DAN15; MRD12; P250R; BRIGHT; BAF250B; ELD/OSA1
Transcripts ENSG00000049618
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors
Uniport_ID Q8NFD5
HGNC ID HGNC:18040
VEGA ID OTTHUMG00000015890
OMIM ID 614556
String ID 9606.ENSP00000344546
PharmGKB ID PA134909463
Target gene [ARID1B] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1002431 chr6 244 19 12 275 View
1008638 chr6 7 6 7 20 View
1008835 chr6 8 7 4 19 View
1015080 chr6 1 2 3 View
1400540 chr6 7 3 2 12 View
1401729 chr6 244 19 12 275 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of ARID1B expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
ARID1B expression: Low -> High
Lollipop of ARID1B expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of ARID1B expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ARID1B expression and immune infiltrating cell level correlation result in HBV+ samples
ARID1B expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).