HIV Target gene Detail Information

> ARHGEF7 Gene Search Result

Gene Information

Gene Name	ARHGEF7
Gene ID	8874
Gene Full Name	Rho guanine nucleotide exchange factor 7
Gene Alias	P50; P85; PAK3; PIXB; COOL1; P50BP; COOL-1; P85SPR; BETA-PIX; P85COOL1; Nbla10314
Transcripts	ENSG00000102606
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q14155
HGNC ID	HGNC:15607
VEGA ID	OTTHUMG00000017357
OMIM ID	605477
String ID	9606.ENSP00000364893
PharmGKB ID	PA24977

Target gene [ARHGEF7] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002929	chr13	39	32	4	75	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ARHGEF7 expression and immune infiltrating cell level correlation result in HIV+ samples
ARHGEF7 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ARHGEF7 expression and immune infiltrating cell level correlation result in HIV+ samples
ARHGEF7 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).