HBV Target gene Detail Information

> ARHGEF37 Gene Search Result


Gene Information
Gene Name ARHGEF37
Gene ID 389337
Gene Full Name Rho guanine nucleotide exchange factor 37
Transcripts ENSG00000183111
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID A1IGU5
HGNC ID HGNC:34430
VEGA ID OTTHUMG00000163491
String ID 9606.ENSP00000328083
PharmGKB ID PA165660135
Target gene [ARHGEF37] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1003134 chr5 143 19 1 163 View
1401571 chr5 143 19 1 163 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ARHGEF37 expression and immune infiltrating cell level correlation result in HBV+ samples
ARHGEF37 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).