HIV Target gene Detail Information

> ARHGEF28 Gene Search Result

Gene Information

Gene Name	ARHGEF28
Gene ID	64283
Gene Full Name	Rho guanine nucleotide exchange factor 28
Gene Alias	RIP2; RGNEF; p190RHOGEF
Transcripts	ENSG00000214944
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Microtubules;Plasma membrane;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q8N1W1
HGNC ID	HGNC:30322
VEGA ID	OTTHUMG00000162454
OMIM ID	612790
String ID	9606.ENSP00000441913
PharmGKB ID	PA166048998

Target gene [ARHGEF28] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002355	chr5	74	21	3	98	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ARHGEF28 expression and immune infiltrating cell level correlation result in HIV+ samples
ARHGEF28 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).