HIV Target gene Detail Information

> ARHGDIA Gene Search Result

Gene Information

Gene Name	ARHGDIA
Gene ID	396
Gene Full Name	Rho GDP dissociation inhibitor alpha
Gene Alias	GDIA1; NPHS8; RHOGDI; RHOGDI-1; HEL-S-47e
Transcripts	ENSG00000141522
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	P52565
HGNC ID	HGNC:678
VEGA ID	OTTHUMG00000178352
OMIM ID	601925
String ID	9606.ENSP00000269321
PharmGKB ID	PA24963

Target gene [ARHGDIA] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001196	chr17	11	172	16	199	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ARHGDIA expression and immune infiltrating cell level correlation result in HIV+ samples
ARHGDIA expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ARHGDIA expression and immune infiltrating cell level correlation result in HIV+ samples
ARHGDIA expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).