HBV Target gene Detail Information

> ARHGAP8 Gene Search Result

Gene Information

Gene Name	ARHGAP8
Gene ID	23779
Gene Full Name	Rho GTPase activating protein 8
Gene Alias	PP610; BPGAP1
Transcripts	ENSG00000241484
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	P85298
HGNC ID	HGNC:677
VEGA ID	OTTHUMG00000030234
OMIM ID	609405
String ID	9606.ENSP00000374424
PharmGKB ID	PA24961

Target gene [ARHGAP8] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1001551	chr22	37	471	117	625	View
1404671	chr22	31	3		34	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of ARHGAP8 expression and immune infiltrating cell level correlation result in HBV+ samples
ARHGAP8 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).