HIV Target gene Detail Information

> ARHGAP5 Gene Search Result

Gene Information

Gene Name	ARHGAP5
Gene ID	394
Gene Full Name	Rho GTPase activating protein 5
Gene Alias	GFI2; p190-B; RhoGAP5; p190BRhoGAP
Transcripts	ENSG00000100852
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Endoplasmic reticulum;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q13017
HGNC ID	HGNC:675
VEGA ID	OTTHUMG00000170589
OMIM ID	602680
String ID	9606.ENSP00000371897
PharmGKB ID	PA24959

Target gene [ARHGAP5] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003921	chr14	49	3		52	View
4014855	chr14		2		2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ARHGAP5 expression and immune infiltrating cell level correlation result in HIV+ samples
ARHGAP5 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).