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HBV Target gene Detail Information

> ARHGAP42 Gene Search Result


Gene Information
Gene Name ARHGAP42
Gene ID 143872
Gene Full Name Rho GTPase activating protein 42
Gene Alias AD031; GRAF3; TMEM133
Transcripts ENSG00000165895
Virus HBV
Gene Type protein coding
HPA Location Info Nuclear speckles;Cytosol;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID A6NI28; Q9H2Q1
HGNC ID HGNC:26545
VEGA ID OTTHUMG00000167530
OMIM ID 615936
String ID 9606.ENSP00000298815
PharmGKB ID PA165543186
Target gene [ARHGAP42] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1005921 chr11 18 6 22 46 View
1009740 chr11 12 2 14 View
1012710 chr11 6 6 View
1016277 chr11 1 1 View
1403350 chr11 1 1 View
1403745 chr11 12 2 14 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ARHGAP42 expression and immune infiltrating cell level correlation result in HBV+ samples
ARHGAP42 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).