HIV Target gene Detail Information

> ARHGAP35 Gene Search Result

Gene Information

Gene Name	ARHGAP35
Gene ID	2909
Gene Full Name	Rho GTPase activating protein 35
Gene Alias	GRF-1; GRLF1; P190A; P190-A; p190RhoGAP; p190ARhoGAP
Transcripts	ENSG00000160007
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear bodies;Aggresome;
HPA Protein Class Info	Cancer-related genes, Predicted intracellular proteins
Uniport_ID	Q9NRY4
HGNC ID	HGNC:4591
VEGA ID	OTTHUMG00000183438
OMIM ID	605277
String ID	9606.ENSP00000385720
PharmGKB ID	PA28988

Target gene [ARHGAP35] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000311	chr19	73	260	223	556	View
4005120	chr19	25	7	3	35	View
4005121	chr19	25	7	3	35	View
4005122	chr19	25	7	3	35	View
4005123	chr19	25	7	3	35	View
4007201	chr19	11	5	3	19	View
4010047	chr19	10			10	View
4012276	chr19	5			5	View
4015084	chr19	1			1	View
4016726	chr19				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ARHGAP35 expression and immune infiltrating cell level correlation result in HIV+ samples
ARHGAP35 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).