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HIV Target gene Detail Information

> ARHGAP26 Gene Search Result


Gene Information
Gene Name ARHGAP26
Gene ID 23092
Gene Full Name Rho GTPase activating protein 26
Gene Alias GRAF; GRAF1; OPHN1L; OPHN1L1
Transcripts ENSG00000145819
Virus HIV
Gene Type protein coding
HPA Location Info Cytosol;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q9UNA1
HGNC ID HGNC:17073
VEGA ID OTTHUMG00000059705
OMIM ID 605370
String ID 9606.ENSP00000274498
PharmGKB ID PA134946198
Target gene [ARHGAP26] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4000184 chr5 619 66 116 801 View
4005176 chr5 22 8 5 35 View
4013014 chr5 3 1 4 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of ARHGAP26 expression and immune infiltrating cell level correlation result in HIV+ samples
ARHGAP26 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of ARHGAP26 expression and immune infiltrating cell level correlation result in HIV+ samples
ARHGAP26 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).