HIV Target gene Detail Information

> ARHGAP12 Gene Search Result


Gene Information
Gene Name ARHGAP12
Gene ID 94134
Gene Full Name Rho GTPase activating protein 12
Transcripts ENSG00000165322
Virus HIV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q8IWW6
HGNC ID HGNC:16348
VEGA ID OTTHUMG00000017911
OMIM ID 610577
String ID 9606.ENSP00000345808
PharmGKB ID PA24957
Target gene [ARHGAP12] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4008726 chr10 1 13 14 View
4011434 chr10 5 1 1 7 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of ARHGAP12 expression and immune infiltrating cell level correlation result in HIV+ samples
ARHGAP12 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of ARHGAP12 expression and immune infiltrating cell level correlation result in HIV+ samples
ARHGAP12 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).