HIV Target gene Detail Information

> ARHGAP1 Gene Search Result

Gene Information

Gene Name	ARHGAP1
Gene ID	392
Gene Full Name	Rho GTPase activating protein 1
Gene Alias	RHOGAP; RHOGAP1; CDC42GAP; p50rhoGAP
Transcripts	ENSG00000175220
Virus	HIV
Gene Type	protein coding
HPA Location Info	Vesicles;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q07960
HGNC ID	HGNC:673
VEGA ID	OTTHUMG00000166567
OMIM ID	602732
String ID	9606.ENSP00000310491
PharmGKB ID	PA24956

Target gene [ARHGAP1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003589	chr11	38	20		58	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ARHGAP1 expression and immune infiltrating cell level correlation result in HIV+ samples
ARHGAP1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ARHGAP1 expression and immune infiltrating cell level correlation result in HIV+ samples
ARHGAP1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).